A/Prof Jeanne Tie is the lower gastrointestinal medical oncology and trials lead at the Peter MacCallum Cancer Centre and senior research fellow in the Personalised Oncology Division at the Walter and Eliza Hall Institute of Medical Research. Stephanie and A/Prof Tie discuss personalising treatment for bowel cancer patients using prognostic and predictive biomarkers, including circulating tumour DNA.A/Prof Tie is passionate about the new frontier of cancer, the opportunities to improve patient outcomes and the importance of research and clinical trials.