MassLive's Karen Guregian joins the show to make the case for and against the Patriots being the best team in the AFC. Later, Andrew and Karen preview Monday night's game against the Giants, explain why the Pats are on upset alert, and make their game picks. Pats Interference is Powered by:  Prize Picks - https://prizepicks.onelink.me/LME0/CLNS Sign up at http://prizepicks.onelink.me/LME0/CLNS & Download the app today and use code CLNS to get $50 in lineups after you play your first $5 lineup! Learn more about your ad choices. Visit megaphone.fm/adchoices