From Pharma to Future: How Bold Leadership Transformed Pluri

What does it take to lead transformation when everything—including identity—must change? Yaky Yanay, CEO of Pluri, joins Felicia Shakiba for a powerful Season 3 finale conversation on leading transformation through trust, transparency, and bold vision. Yaky shares how he redefined Pluri’s identity—from a traditional pharma company to a cell-based technology innovator—while building a culture that puts people, purpose, and innovation at the center of change. This episode explores how leadership courage, disciplined decision making, and clear C-suite strategy enable successful transformation in high-stakes environments. Yaky explains why trust and transparency are not soft ideals but critical drivers of value creation—and how aligning culture, communication, and execution allows organizations to scale innovation. The conversation highlights how digital transformation, enterprise technology, and thoughtful business process automation support reinvention without losing the human core. Chapters 00:00 The Importance of Culture in Leadership 12:11 Navigating Organizational Transformation 17:53 Overcoming Resistance to Change 26:47 Building Trust Through Transparency 31:05 Expanding Vision Without Losing Focus 36:45 Advice for Leaders in Times of Change — Subscribe to the LeaderbookAI Podcast (formerly CPO PLAYBOOK): https://leaderbook.ai/podcast Want to create 10x the value of your business or investments? Let’s talk: https://leaderbook.ai/contact