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Brain's Sanitation Department

Science up!

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Episode  ·  18:29  ·  Feb 23, 2025

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Ever wondered how your brain takes out the trash? In this episode of Science Up!, we dive into the brain's waste disposal system—the glymphatic system—and how it keeps your neurons squeaky clean. But here's the twist: aging slows down this clean-up crew, potentially leading to cognitive decline. Key Takeaways:✅ The glymphatic system flushes out metabolic waste using cerebrospinal fluid (CSF).✅ Aging disrupts blood flow, slows CSF circulation, and weakens immune clearance, making waste disposal less efficient.✅ Poor sleep impairs brain cleaning, linking sleep deprivation to neurodegenerative diseases.✅ Meningeal lymphatic vessels shrink with age, reducing CSF drainage efficiency.✅ White matter integrity declines, affecting brain connectivity and cognitive speed.The episode was hosted by Niraj Gupta & Muskan Mittal. The Science up! podcast is now streaming on all music/podcast platforms like Spotify, Apple Podcasts, Gaana, JioSaavn. So Don't wait, go Science up! yourself!!#Neuroscience #BrainHealth #GlymphaticSystem #AgingBrain #CognitiveDecline #Neuroimmunology #ScienceUp!

18m 29s  ·  Feb 23, 2025

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