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Andrew Pieper: Recent Evidence that Advanced Alzheimer's Disease May be Reversible

BRAIN PONDERINGS

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Episode  ·  59:26  ·  Jan 6, 2026

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In this episode I talk with Case Western Reserve University Professor Andrew Pieper about how it might be possible to restore neuroplasticity and cognition in Alzheimer's disease. The conversation focuses on a recently published study from his laboratory which shows that a chemical called P7C3-A20 that restores energy balance in brain cells can reverse brain pathology and restore cognitive function in a mouse model of Alzheimer's disease.   LINKS Pieper laboratory: https://www.harringtondiscovery.org/about/harrington-investigators/andrew-pieper-lab Article discussed in this podcast: https://www.cell.com/action/showPdf?pii=S2666-3791%2825%2900608-1

59m 26s  ·  Jan 6, 2026

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